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Common Prescription Medications being Studied as Possible Treatments for Methamphetamine Addiction


The abuse of the drug Methamphetamine also known as meth, ice, speed, crystal meth, and crank has researchers and scientists looking into the use of commonly prescribed medications for several different diseases as a treatment to help meth addicts overcome their addiction.

Clinical Trials / The Treatment Plan

Part of the treatment program requires the addict to attend at least a 30-day rehab and detoxification program first. In this study, there are approximately 800 participants. In addition, to the rehab and detoxification each participant must also under go cognitive behavioral therapy to first understand what meth does to the body beyond the “feel good” phase, the participants also learn why they use meth and work with a therapist to help them overcome the physiological issues that encourage them to continue to abuse meth.

Prescription Medications Being Tested for Treatment

One of the prescription medications being looked at to help meth addicts is a group of medications that fall into the antidepressant group of medications.


Antidepressants increase the serotonin in the brain, this neurotransmitter with pleasure. Antidepressants are also currently being used in a clinical trial setting to treat recovering meth addicts to help with the depression, which is often a withdrawal symptom. These medications are also being used to help prevent a relapse.

Blood Pressure Medications

High blood pressure medications (calcium-channel blockers) are also being tested. The medication releases an excessive amount of neurotransmitters that reduce the reward feeling of using meth.

Medications to Help with Relapse

There are a few medications being tested for relapse those include the drug Zofran, an anti-nausea medication that has already proven to work with alcohol addiction. Tyrosine, an amino acid that is a precursor to the neurotransmitter dopamine, which releases the “feel good” sensation.

Anti-Smoking Medications Being Considered

Anti-smoking medications such as Wellbutrin and Zyban are currently in the research stages to see how much of an effect they will have on helping a meth addict quit or if this class of drugs is better suited for withdrawal symptoms.